Our main goal in this text will be to understand why all these chains of neuronal structures exist, how they work, and what they do. We want to know what kind of visual information travels along a trunk of fibers, and how the information is modified in each region--retina, lateral geniculate body, and the various levels of cortex. We attack the problem by using the microelectrode, the single most important tool in the modern era of neurophysiology. We insert the microelectrode (usually a fine insulated wire) into whatever structure we wish to study--for example, the lateral geniculate body--so that its tip comes close enough to a cell to pick up its electrical signals. We attempt to influence those signals by shining spots or patterns of light on the animal's retina. An experimental plan for recording from the visual pathway. The animal, usually a macaque monkey, faces a screen onto which we project a stimulus. We record by inserting a microelectrode into some part of the pathway, in this case, the primary visual cortex. (The brain in this diagram is from a human, but a monkey brain is very similar.) Because the lateral geniculate body receives its main input from the retina, each cell in the geniculate will receive connections from rods and cones--not directly but by way of intermediate retinal cells. As you will see in Chapter 3, the population of rods and cones that feed into a given cell in the visual pathway are not scattered about all over the retina but are clustered into a small area. This area of the retina is called the receptive field of the cell. So our first step, in shining the light here and there on the retina, is to find the cell's receptive field. Once we have defined the receptive field's boundaries, we can begin to vary the shape, size, color, and rate of movement of the stimulus--to learn what kinds of visual stimuli cause the cell to respond best.